This cross-sectional study included 122 eyes of 61 women, divided into two groups: 27 healthy pregnant women in the third trimester and 34 age-matched healthy non-pregnant women. The aim of this study was to compare choroidal thickness measurements of healthy women, pregnant and non-pregnant, using EDI-OCT. Since it is a noninvasive diagnostic method, EDI-OCT would be ideal for the study of choroid changes during an uncomplicated pregnancy. EDI-OCT promotes better documentation of the choroid and choroidal–scleral interface by decreasing signal strength posterior to the retinal pigment epithellium. The development of the enhanced depth imaging (EDI) technique of spectral-domain optical coherence tomography (SD-OCT) systems allowed analysis of choroidal morphologic features in normal and pathological eyes. Choroidal dysfunction and ischemia are also a common ocular complication of preeclampsia. A strong association of central serous chorioretinopathy and pregnancy is well documented. The impact of pregnancy on the choroid, however, is still under investigation, with mixed results. Changes in ocular blood flow may also occur, as an increased pulsatile ocular blood flow. Ocular changes during pregnancy like an increased central corneal thickness and curvature and decreased corneal sensitivity and intraocular pressure (IOP) were already described. Cardiac output is increased as early as the 5th week and reflects a reduced systemic vascular resistance and an increased heart rate. Volemia augmentation in pregnancy averages 40–45% above the nonpregnant blood volume after 32–34 weeks. Physiological changes during pregnancy are significant and their knowledge is essential to optimize outcomes. Our study showed no statistically difference in choroidal thickness between healthy non-pregnant women and healthy pregnant women in the third trimester. There was also no statistically significant association between gestational age and choroidal thickness measurements in the healthy pregnant women group. Mean subfoveal choroidal thickness was 304.1 + 9.6 µm in the control group and 318.1 + 15.6 µm in the pregnant women group (p = 0.446). There were no significant differences in the ten measurements of choroidal thickness comparing both groups. Choroidal thickness was measured using Enhanced Depth Imaging OCT at ten different locations: at the fovea and every 500 µm from the fovea up to 2500 µm temporally and up to 2000 µm nasally. The aim of this study is to compare choroidal thickness measurements of healthy pregnant women in the third trimester and healthy non-pregnant women using spectral-domain optical coherence tomography (OCT). For now, it is a great medical and government tool that is slowly making its way into the commercial realm.The impact of pregnancy on the choroid is still under investigation. As time passes, medicine and modern technology may find more ways to use the retina scan. From pregnancy to malaria, AIDs, chicken pox, and Lyme disease, retina scans could be use to help diagnose and monitor the patient’s progress. Many health conditions and diseases alter the eyes. In terms of medicine, the retina scan can serve another purpose. A number of government organizations, such as the CIA, NASA, and the FBI, already use retina scan technology. Overall, retina scans are used for identification and authentication. Retina scan technology is slowly becoming more accessible and more commercial implementations have been found. For now, the retina scan may be a bit advanced even by modern standards, for it to be a cost effective authentication solution. The equipment required costs a lot and some people do not like how intrusive the entire retina scan process feels. Unfortunately, retina scan results can be altered if the person being scanned develops an eye disease or severe astigmatism. The process also works quickly, with results given right away. No two individuals share the same retinal patterns so each retina scan is unique. The technology is also considered very reliable because it is so accurate. The use of the retina scan helps lower the chances for a false positive or negative. It wasn’t until four decades later in 1975 that a scanning device was created that could use retina scan technology. It was considered advanced medicine the year it was published in the New York State Journal of Medicine. Isadore Goldstine came up with the concept behind the procedure. A retina scan can help identify an individual using the unique patterns found in their retina.
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